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Therapeutic potential of a dual mTORC1/2 inhibitor for the prevention of posterior capsule opacification: An in vitro study

Mammalian target of rapamycin (mTOR) serves a central role in regulating cell growth and survival, and has been demonstrated to be involved in the pathological progression of posterior capsule opacification (PCO). In the present study, the potency of PP242, a novel dual inhibitor of mTOR complex 1/2...

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Detalles Bibliográficos
Autores principales: Feng, Hao, Yang, Zhibo, Bai, Xue, Yang, Meirong, Fang, Yuan, Zhang, Xiaonan, Guo, Qiqiang, Ning, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810205/
https://www.ncbi.nlm.nih.gov/pubmed/29344639
http://dx.doi.org/10.3892/ijmm.2018.3398