Histone deacetylase-4 and histone deacetylase-8 regulate interleukin-1β-induced cartilage catabolic degradation through MAPK/JNK and ERK pathways

Interleukin-1β (IL-1β)-induced inflammatory response is associated with osteoarthritis (OA) and its development. Histone deacetylase (HDAC) may be involved in regulating this pathogenesis, but the mechanism has yet to be elucidated. The aim of the present study was to investigate the mechanism under...

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Detalles Bibliográficos
Autores principales: Wang, Pengcheng, Mao, Zekai, Pan, Qiyong, Lu, Rui, Huang, Xiaojian, Shang, Xiaobin, Zhang, Rui, You, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810207/
https://www.ncbi.nlm.nih.gov/pubmed/29393346
http://dx.doi.org/10.3892/ijmm.2018.3410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810207/
https://www.ncbi.nlm.nih.gov/pubmed/29393346
http://dx.doi.org/10.3892/ijmm.2018.3410

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