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Increased expression of sterol regulatory element binding protein-2 alleviates autophagic dysfunction in NAFLD
Sterol regulatory element binding protein-2 (SREBP-2) is an important transcription factor in lipid homeostasis. A previous study showed that SREBP-2 also activated autophagic genes during cell-sterol depletion. Alterations in autophagy are reported to be involved in the pathogenesis of nonalcoholic...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810215/ https://www.ncbi.nlm.nih.gov/pubmed/29336468 http://dx.doi.org/10.3892/ijmm.2018.3389 |