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Increased expression of sterol regulatory element binding protein-2 alleviates autophagic dysfunction in NAFLD

Sterol regulatory element binding protein-2 (SREBP-2) is an important transcription factor in lipid homeostasis. A previous study showed that SREBP-2 also activated autophagic genes during cell-sterol depletion. Alterations in autophagy are reported to be involved in the pathogenesis of nonalcoholic...

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Detalles Bibliográficos
Autores principales: Cheng, Chunwei, Deng, Xiaoling, Xu, Keshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810215/
https://www.ncbi.nlm.nih.gov/pubmed/29336468
http://dx.doi.org/10.3892/ijmm.2018.3389