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MicroRNA-139-5p/Flt1/Wnt/β-catenin regulatory crosstalk modulates the progression of glioma

Fms-related tyrosine kinase 1 (Flt1), the receptor of VEGF/PIGF, is associated with cancer angiogenesis and tumorigenesis. Although the high expression of Flt1 in glioma is identified, its regulatory mechanism remains unclear. In the present study, we demonstrate that miR-139-5p inhibits Flt1 expres...

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Detalles Bibliográficos
Autores principales: Wang, Qiong, Xu, Bin, Du, Jixiang, Xu, Xinnv, Shang, Chao, Wang, Xiuyu, Wang, Jinhuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810245/
https://www.ncbi.nlm.nih.gov/pubmed/29393392
http://dx.doi.org/10.3892/ijmm.2018.3439