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Next-Generation Sequencing of Antibody Display Repertoires

In vitro selection technology has transformed the development of therapeutic monoclonal antibodies. Using methods such as phage, ribosome, and yeast display, high affinity binders can be selected from diverse repertoires. Here, we review strategies for the next-generation sequencing (NGS) of phage-...

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Detalles Bibliográficos
Autores principales: Rouet, Romain, Jackson, Katherine J. L., Langley, David B., Christ, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810246/
https://www.ncbi.nlm.nih.gov/pubmed/29472918
http://dx.doi.org/10.3389/fimmu.2018.00118