Senescent T-Cells Promote Bone Loss in Rheumatoid Arthritis

OBJECTIVE: T-cells are critical players in the pathogenesis of osteoporosis in patients with rheumatoid arthritis (RA). Premature senescence of lymphocytes including the accumulation of senescent CD4(+) T-cells is a hallmark feature of RA. Whether T-cell senescence is associated with bone loss in RA...

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Detalles Bibliográficos
Autores principales: Fessler, Johannes, Husic, Rusmir, Schwetz, Verena, Lerchbaum, Elisabeth, Aberer, Felix, Fasching, Patrizia, Ficjan, Anja, Obermayer-Pietsch, Barbara, Duftner, Christina, Graninger, Winfried, Stradner, Martin Helmut, Dejaco, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810289/
https://www.ncbi.nlm.nih.gov/pubmed/29472917
http://dx.doi.org/10.3389/fimmu.2018.00095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810289/
https://www.ncbi.nlm.nih.gov/pubmed/29472917
http://dx.doi.org/10.3389/fimmu.2018.00095

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