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Gp41 and Gag amino acids linked to HIV‐1 protease inhibitor‐based second‐line failure in HIV‐1 subtype A from Western Kenya

INTRODUCTION: Failure of protease‐inhibitor (PI)‐based second‐line antiretroviral therapy (ART) with medication adherence but no protease drug resistance mutations (DRMs) is not well understood. This study investigated the involvement of gp41 and gag as alternative mechanisms, not captured by conven...

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Detalles Bibliográficos
Autores principales: Coetzer, Mia, Ledingham, Lauren, Diero, Lameck, Kemboi, Emmanuel, Orido, Millicent, Kantor, Rami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810327/
https://www.ncbi.nlm.nih.gov/pubmed/29098809
http://dx.doi.org/10.1002/jia2.25024