Plectin deficiency in liver cancer cells promotes cell migration and sensitivity to sorafenib treatment

Plectin involved in activation of kinases in cell signaling pathway and plays important role in cell morphology and migration. Plectin knockdown promotes cell migration by activating focal adhesion kinase and Rac1-GTPase activity in liver cells. Sorafenib is a multi-targeting tyrosine kinase inhibit...

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Detalles Bibliográficos
Autores principales: Cheng, Chiung-Chi, Chao, Wei-Ting, Liao, Chen-Chun, Tseng, Yu-Hui, Lai, Yen-Chang Clark, Lai, Yih-Shyong, Hsu, Yung-Hsiang, Liu, Yi-Hsiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810502/
https://www.ncbi.nlm.nih.gov/pubmed/28276928
http://dx.doi.org/10.1080/19336918.2017.1288789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810502/
https://www.ncbi.nlm.nih.gov/pubmed/28276928
http://dx.doi.org/10.1080/19336918.2017.1288789

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