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Plectin deficiency in liver cancer cells promotes cell migration and sensitivity to sorafenib treatment
Plectin involved in activation of kinases in cell signaling pathway and plays important role in cell morphology and migration. Plectin knockdown promotes cell migration by activating focal adhesion kinase and Rac1-GTPase activity in liver cells. Sorafenib is a multi-targeting tyrosine kinase inhibit...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810502/ https://www.ncbi.nlm.nih.gov/pubmed/28276928 http://dx.doi.org/10.1080/19336918.2017.1288789 |