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Raptor mediates the antiproliferation of cardamonin by mTORC1 inhibition in SKOV3 cells
PURPOSE: Cardamonin inhibits the proliferation of SKOV3 cells by suppressing the mammalian target of rapamycin complex 1 (mTORC1). However, the mechanism of cardamonin on mTORC1 inhibition has not been well demonstrated. The regulatory-associated protein of TOR (Raptor) is an essential component of...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove Medical Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810526/ https://www.ncbi.nlm.nih.gov/pubmed/29445291 http://dx.doi.org/10.2147/OTT.S155065 |