Endoplasmic reticulum chaperone GRP78 mediates cigarette smoke-induced necroptosis and injury in bronchial epithelium

INTRODUCTION: Bronchial epithelial cell death and airway inflammation induced by cigarette smoke (CS) have been involved in the pathogenesis of COPD. GRP78, belonging to heat shock protein 70 family, has been implicated in cell death and inflammation, while little is known about its roles in COPD. H...

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Detalles Bibliográficos
Autores principales: Wang, Yong, Zhou, Jie-Sen, Xu, Xu-Chen, Li, Zhou-Yang, Chen, Hai-Pin, Ying, Song-Min, Li, Wen, Shen, Hua-Hao, Chen, Zhi-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810534/
https://www.ncbi.nlm.nih.gov/pubmed/29445274
http://dx.doi.org/10.2147/COPD.S150633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810534/
https://www.ncbi.nlm.nih.gov/pubmed/29445274
http://dx.doi.org/10.2147/COPD.S150633

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