Orphan G protein-coupled receptor GPRC5A modulates integrin β1-mediated epithelial cell adhesion

G-Protein Coupled Receptor (GPCR), Class C, Group 5, Member A (GPRC5A) has been implicated in several malignancies. The underlying mechanisms, however, remain poorly understood. Using a panel of human cell lines, we demonstrate that CRISPR/Cas9-mediated knockout and RNAi-mediated depletion of GPRC5A...

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Detalles Bibliográficos
Autores principales: Bulanova, Daria R., Akimov, Yevhen A., Rokka, Anne, Laajala, Teemu D., Aittokallio, Tero, Kouvonen, Petri, Pellinen, Teijo, Kuznetsov, Sergey G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810789/
https://www.ncbi.nlm.nih.gov/pubmed/27715394
http://dx.doi.org/10.1080/19336918.2016.1245264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810789/
https://www.ncbi.nlm.nih.gov/pubmed/27715394
http://dx.doi.org/10.1080/19336918.2016.1245264

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