Stabilization of NF-κB-Inducing Kinase Suppresses MLL-AF9-Induced Acute Myeloid Leukemia

Canonical NF-κB signaling is constitutively activated in acute myeloid leukemia (AML) stem cells and is required for maintenance of the self-renewal of leukemia stem cells (LSCs). However, any potential role for NF-κB non-canonical signaling in AML has been largely overlooked. Here, we report that s...

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Detalles Bibliográficos
Autores principales: Xiu, Yan, Dong, Qianze, Li, Qingchang, Li, Fengyin, Borcherding, Nick, Zhang, Weizhou, Boyce, Brendan, Xue, Hai-hui, Zhao, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810947/
https://www.ncbi.nlm.nih.gov/pubmed/29320732
http://dx.doi.org/10.1016/j.celrep.2017.12.055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810947/
https://www.ncbi.nlm.nih.gov/pubmed/29320732
http://dx.doi.org/10.1016/j.celrep.2017.12.055

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