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Highly conserved extended haplotypes of the major histocompatibility complex and their relationship to multiple sclerosis susceptibility

OBJECTIVE: To determine the relationship between highly-conserved extended-haplotypes (CEHs) in the major histocompatibility complex (MHC) and MS-susceptibility. BACKGROUND: Among the ~200 MS-susceptibility regions, which are known from genome-wide analyses of single nucleotide polymorphisms (SNPs),...

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Detalles Bibliográficos
Autores principales: Goodin, Douglas S., Khankhanian, Pouya, Gourraud, Pierre-Antoine, Vince, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810982/
https://www.ncbi.nlm.nih.gov/pubmed/29438392
http://dx.doi.org/10.1371/journal.pone.0190043