Cargando…

The siRNA-mediated knockdown of GluN3A in 46C-derived neural stem cells affects mRNA expression levels of neural genes, including known iGluR interactors

For years, GluN3A was solely considered to be a dominant-negative modulator of NMDARs, since its incorporation into receptors alters hallmark features of conventional NMDARs composed of GluN1/GluN2 subunits. Only recently, increasing evidence has accumulated that GluN3A plays a more diversified role...

Descripción completa

Detalles Bibliográficos
Autores principales: Pachernegg, Svenja, Eilebrecht, Sebastian, Eilebrecht, Elke, Schöneborn, Hendrik, Neumann, Sebastian, Benecke, Arndt G., Hollmann, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811004/
https://www.ncbi.nlm.nih.gov/pubmed/29438442
http://dx.doi.org/10.1371/journal.pone.0192242