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The siRNA-mediated knockdown of GluN3A in 46C-derived neural stem cells affects mRNA expression levels of neural genes, including known iGluR interactors
For years, GluN3A was solely considered to be a dominant-negative modulator of NMDARs, since its incorporation into receptors alters hallmark features of conventional NMDARs composed of GluN1/GluN2 subunits. Only recently, increasing evidence has accumulated that GluN3A plays a more diversified role...
Autores principales: | Pachernegg, Svenja, Eilebrecht, Sebastian, Eilebrecht, Elke, Schöneborn, Hendrik, Neumann, Sebastian, Benecke, Arndt G., Hollmann, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811004/ https://www.ncbi.nlm.nih.gov/pubmed/29438442 http://dx.doi.org/10.1371/journal.pone.0192242 |
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