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Tissue distribution and subcellular localizations determine in vivo functional relationship among prostasin, matriptase, HAI-1, and HAI-2 in human skin

The membrane-bound serine proteases prostasin and matriptase and the Kunitz-type protease inhibitors HAI-1 and HAI-2 are all expressed in human skin and may form a tightly regulated proteolysis network, contributing to skin pathophysiology. Evidence from other systems, however, suggests that the rel...

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Detalles Bibliográficos
Autores principales: Lee, Shiao-Pieng, Kao, Chen-Yu, Chang, Shun-Cheng, Chiu, Yi-Lin, Chen, Yen-Ju, Chen, Ming-Hsing G., Chang, Chun-Chia, Lin, Yu-Wen, Chiang, Chien-Ping, Wang, Jehng-Kang, Lin, Chen-Yong, Johnson, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811018/
https://www.ncbi.nlm.nih.gov/pubmed/29438412
http://dx.doi.org/10.1371/journal.pone.0192632