Identification and characterization of MYH9 locus for high efficient gene knock-in and stable expression in mouse embryonic stem cells

Targeted integration of exogenous genes into so-called safe harbors/friend sites, offers the advantages of expressing normal levels of target genes and preventing potentially adverse effects on endogenous genes. However, the ideal genomic loci for this purpose remain limited. Additionally, due to th...

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Detalles Bibliográficos
Autores principales: Liu, Tanbin, Hu, Yi, Guo, Shiyin, Tan, Lei, Zhan, Yang, Yang, Lingchen, Liu, Wei, Wang, Naidong, Li, Yalan, Zhang, Yingfan, Liu, Chengyu, Yang, Yi, Adelstein, Robert S., Wang, Aibing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811019/
https://www.ncbi.nlm.nih.gov/pubmed/29438440
http://dx.doi.org/10.1371/journal.pone.0192641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811019/
https://www.ncbi.nlm.nih.gov/pubmed/29438440
http://dx.doi.org/10.1371/journal.pone.0192641

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