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Olig2 and Hes regulatory dynamics during motor neuron differentiation revealed by single cell transcriptomics

During tissue development, multipotent progenitors differentiate into specific cell types in characteristic spatial and temporal patterns. We addressed the mechanism linking progenitor identity and differentiation rate in the neural tube, where motor neuron (MN) progenitors differentiate more rapidl...

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Detalles Bibliográficos
Autores principales: Sagner, Andreas, Gaber, Zachary B., Delile, Julien, Kong, Jennifer H., Rousso, David L., Pearson, Caroline A., Weicksel, Steven E., Melchionda, Manuela, Mousavy Gharavy, S. Neda, Briscoe, James, Novitch, Bennett G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811045/
https://www.ncbi.nlm.nih.gov/pubmed/29389974
http://dx.doi.org/10.1371/journal.pbio.2003127