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Olig2 and Hes regulatory dynamics during motor neuron differentiation revealed by single cell transcriptomics
During tissue development, multipotent progenitors differentiate into specific cell types in characteristic spatial and temporal patterns. We addressed the mechanism linking progenitor identity and differentiation rate in the neural tube, where motor neuron (MN) progenitors differentiate more rapidl...
Autores principales: | Sagner, Andreas, Gaber, Zachary B., Delile, Julien, Kong, Jennifer H., Rousso, David L., Pearson, Caroline A., Weicksel, Steven E., Melchionda, Manuela, Mousavy Gharavy, S. Neda, Briscoe, James, Novitch, Bennett G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811045/ https://www.ncbi.nlm.nih.gov/pubmed/29389974 http://dx.doi.org/10.1371/journal.pbio.2003127 |
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