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Evolutionary analysis of polyproline motifs in Escherichia coli reveals their regulatory role in translation

Translation of consecutive prolines causes ribosome stalling, which is alleviated but cannot be fully compensated by the elongation factor P. However, the presence of polyproline motifs in about one third of the E. coli proteins underlines their potential functional importance, which remains largely...

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Detalles Bibliográficos
Autores principales: Qi, Fei, Motz, Magdalena, Jung, Kirsten, Lassak, Jürgen, Frishman, Dmitrij
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811046/
https://www.ncbi.nlm.nih.gov/pubmed/29389943
http://dx.doi.org/10.1371/journal.pcbi.1005987