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Evolutionary analysis of polyproline motifs in Escherichia coli reveals their regulatory role in translation
Translation of consecutive prolines causes ribosome stalling, which is alleviated but cannot be fully compensated by the elongation factor P. However, the presence of polyproline motifs in about one third of the E. coli proteins underlines their potential functional importance, which remains largely...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811046/ https://www.ncbi.nlm.nih.gov/pubmed/29389943 http://dx.doi.org/10.1371/journal.pcbi.1005987 |