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A switch in the mode of Wnt signaling orchestrates the formation of germline stem cell differentiation niche in Drosophila
Germline stem cell (GSC) self-renewal and differentiation into gametes is regulated by both intrinsic factors in the germ line as well as extrinsic factors from the surrounding somatic niche. dWnt4, in the escort cells of the adult somatic niche promotes GSC differentiation using the canonical β-cat...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811049/ https://www.ncbi.nlm.nih.gov/pubmed/29370168 http://dx.doi.org/10.1371/journal.pgen.1007154 |