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A switch in the mode of Wnt signaling orchestrates the formation of germline stem cell differentiation niche in Drosophila

Germline stem cell (GSC) self-renewal and differentiation into gametes is regulated by both intrinsic factors in the germ line as well as extrinsic factors from the surrounding somatic niche. dWnt4, in the escort cells of the adult somatic niche promotes GSC differentiation using the canonical β-cat...

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Detalles Bibliográficos
Autores principales: Upadhyay, Maitreyi, Kuna, Michael, Tudor, Sara, Martino Cortez, Yesenia, Rangan, Prashanth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811049/
https://www.ncbi.nlm.nih.gov/pubmed/29370168
http://dx.doi.org/10.1371/journal.pgen.1007154