Directed evolution of GFP with non-natural amino acids identifies residues for augmenting and photoswitching fluorescence

Genetic code reprogramming allows proteins to sample new chemistry through the defined and targeted introduction of non-natural amino acids (nAAs). Many useful nAAs are derivatives of the natural aromatic amino acid tyrosine, with the para OH group replaced with useful but often bulkier substituents...

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Detalles Bibliográficos
Autores principales: Reddington, Samuel C., Baldwin, Amy J., Thompson, Rebecca, Brancale, Andrea, Tippmann, Eric M., Jones, D. Dafydd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811120/
https://www.ncbi.nlm.nih.gov/pubmed/29560203
http://dx.doi.org/10.1039/c4sc02827a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811120/
https://www.ncbi.nlm.nih.gov/pubmed/29560203
http://dx.doi.org/10.1039/c4sc02827a

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