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Enzymatic modification of 5′-capped RNA with a 4-vinylbenzyl group provides a platform for photoclick and inverse electron-demand Diels–Alder reaction

Chemo-enzymatic strategies provide a highly selective means to label different classes of biomolecules in vitro, but also in vivo. In the field of RNA, efficient labeling of eukaryotic mRNA with small organic reporter molecules would provide a way to detect endogenous mRNA and is therefore highly at...

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Detalles Bibliográficos
Autores principales: Holstein, Josephin Marie, Stummer, Daniela, Rentmeister, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811123/
https://www.ncbi.nlm.nih.gov/pubmed/29560223
http://dx.doi.org/10.1039/c4sc03182b