Chelation-induced diradical formation as an approach to modulation of the amyloid-β aggregation pathway

Current approaches toward modulation of metal-induced Aβ aggregation pathways involve the development of small molecules that bind metal ions, such as Cu(ii) and Zn(ii), and interact with Aβ. For this effort, we present the enediyne-containing ligand (Z)-N,N′-bis[1-pyridin-2-yl-meth(E)-ylidene]oct-4...

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Detalles Bibliográficos
Autores principales: Porter, Meghan R., Kochi, Akiko, Karty, Jonathan A., Lim, Mi Hee, Zaleski, Jeffrey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811126/
https://www.ncbi.nlm.nih.gov/pubmed/29560189
http://dx.doi.org/10.1039/c4sc01979b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811126/
https://www.ncbi.nlm.nih.gov/pubmed/29560189
http://dx.doi.org/10.1039/c4sc01979b

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