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KIF2A regulates the development of dentate granule cells and postnatal hippocampal wiring

Kinesin super family protein 2A (KIF2A), an ATP-dependent microtubule (MT) destabilizer, regulates cell migration, axon elongation, and pruning in the developing nervous system. KIF2A mutations have recently been identified in patients with malformed cortical development. However, postnatal KIF2A is...

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Detalles Bibliográficos
Autores principales: Homma, Noriko, Zhou, Ruyun, Naseer, Muhammad Imran, Chaudhary, Adeel G, Al-Qahtani, Mohammed H, Hirokawa, Nobutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811213/
https://www.ncbi.nlm.nih.gov/pubmed/29313800
http://dx.doi.org/10.7554/eLife.30935