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Multivesicular bodies mediate long-range retrograde NGF-TrkA signaling

The development of neurons in the peripheral nervous system is dependent on target-derived, long-range retrograde neurotrophic factor signals. The prevailing view is that target-derived nerve growth factor (NGF), the prototypical neurotrophin, and its receptor TrkA are carried retrogradely by early...

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Detalles Bibliográficos
Autores principales: Ye, Mengchen, Lehigh, Kathryn M, Ginty, David D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811214/
https://www.ncbi.nlm.nih.gov/pubmed/29381137
http://dx.doi.org/10.7554/eLife.33012