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Multivesicular bodies mediate long-range retrograde NGF-TrkA signaling
The development of neurons in the peripheral nervous system is dependent on target-derived, long-range retrograde neurotrophic factor signals. The prevailing view is that target-derived nerve growth factor (NGF), the prototypical neurotrophin, and its receptor TrkA are carried retrogradely by early...
Autores principales: | Ye, Mengchen, Lehigh, Kathryn M, Ginty, David D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811214/ https://www.ncbi.nlm.nih.gov/pubmed/29381137 http://dx.doi.org/10.7554/eLife.33012 |
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