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The Primodos components Norethisterone acetate and Ethinyl estradiol induce developmental abnormalities in zebrafish embryos

Primodos was a hormone pregnancy test used between 1958–1978 that has been implicated with causing a range of birth defects ever since. Though Primodos is no longer used, it’s components, Norethisterone acetate and Ethinyl estradiol, are used in other medications today including treatments for endom...

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Detalles Bibliográficos
Autores principales: Brown, Samantha, Fraga, Lucas Rosa, Cameron, Gary, Erskine, Lynda, Vargesson, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811427/
https://www.ncbi.nlm.nih.gov/pubmed/29440757
http://dx.doi.org/10.1038/s41598-018-21318-9