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Highly variable contractile performance correlates with myocyte content in trabeculae from failing human hearts

Heart failure (HF) is defined by compromised contractile function and is associated with changes in excitation-contraction (EC) coupling and cardiomyocyte organisation. Tissue level changes often include fibrosis, while changes within cardiomyocytes often affect structures critical to EC coupling, i...

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Detalles Bibliográficos
Autores principales: Munro, Michelle L., Shen, Xin, Ward, Marie, Ruygrok, Peter N., Crossman, David J., Soeller, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811450/
https://www.ncbi.nlm.nih.gov/pubmed/29440728
http://dx.doi.org/10.1038/s41598-018-21199-y