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Highly variable contractile performance correlates with myocyte content in trabeculae from failing human hearts
Heart failure (HF) is defined by compromised contractile function and is associated with changes in excitation-contraction (EC) coupling and cardiomyocyte organisation. Tissue level changes often include fibrosis, while changes within cardiomyocytes often affect structures critical to EC coupling, i...
Autores principales: | Munro, Michelle L., Shen, Xin, Ward, Marie, Ruygrok, Peter N., Crossman, David J., Soeller, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811450/ https://www.ncbi.nlm.nih.gov/pubmed/29440728 http://dx.doi.org/10.1038/s41598-018-21199-y |
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