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Reverse Engineering the Intracellular Self-Assembly of a Functional Mechanopharmaceutical Device

Weakly basic, poorly soluble chemical agents could be exploited as building blocks for constructing sophisticated molecular devices inside the cells of living organisms. Here, using experimental and computational approaches, we probed the relationship between the biological mechanisms mediating lyso...

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Detalles Bibliográficos
Autores principales: Woldemichael, Tehetina, Keswani, Rahul K., Rzeczycki, Phillip M., Murashov, Mikhail D., LaLone, Vernon, Gregorka, Brian, Swanson, Joel A., Stringer, Kathleen A., Rosania, Gus R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811454/
https://www.ncbi.nlm.nih.gov/pubmed/29440773
http://dx.doi.org/10.1038/s41598-018-21271-7