Folic Acid Exposure Rescues Spina Bifida Aperta Phenotypes in Human Induced Pluripotent Stem Cell Model

Neural tube defects (NTDs) are severe congenital abnormalities, caused by failed closure of neural tube during early embryonic development. Periconceptional folic acid (FA) supplementation greatly reduces the risk of NTDs. However, the molecular mechanisms behind NTDs and the preventive role of FA r...

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Detalles Bibliográficos
Autores principales: Sahakyan, Vardine, Duelen, Robin, Tam, Wai Long, Roberts, Scott J., Grosemans, Hanne, Berckmans, Pieter, Ceccarelli, Gabriele, Pelizzo, Gloria, Broccoli, Vania, Deprest, Jan, Luyten, Frank P., Verfaillie, Catherine M., Sampaolesi, Maurilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811493/
https://www.ncbi.nlm.nih.gov/pubmed/29440666
http://dx.doi.org/10.1038/s41598-018-21103-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811493/
https://www.ncbi.nlm.nih.gov/pubmed/29440666
http://dx.doi.org/10.1038/s41598-018-21103-8

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