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Identification of Chloride Channels CLCN3 and CLCN5 Mediating the Excitatory Cl(−) Currents Activated by Sphingosine-1-Phosphate in Sensory Neurons
Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid involved in numerous physiological and pathophysiological processes. We have previously reported a S1P-induced nocifensive response in mice by excitation of sensory neurons via activation of an excitatory chloride current. The underlying mole...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811518/ https://www.ncbi.nlm.nih.gov/pubmed/29479306 http://dx.doi.org/10.3389/fnmol.2018.00033 |