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In vitro patient-derived 3D mesothelioma tumor organoids facilitate patient-centric therapeutic screening

Variability in patient response to anti-cancer drugs is currently addressed by relating genetic mutations to chemotherapy through precision medicine. However, practical benefits of precision medicine to therapy design are less clear. Even after identification of mutations, oncologists are often left...

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Detalles Bibliográficos
Autores principales: Mazzocchi, Andrea R., Rajan, Shiny A. P., Votanopoulos, Konstantinos I., Hall, Adam R., Skardal, Aleksander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811529/
https://www.ncbi.nlm.nih.gov/pubmed/29440675
http://dx.doi.org/10.1038/s41598-018-21200-8