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The small GTPase RhoU lays downstream of JAK/STAT signaling and mediates cell migration in multiple myeloma

Multiple myeloma is a post-germinal center B-cell neoplasm, characterized by the proliferation of malignant bone marrow plasma cells, whose survival and proliferation is sustained by growth factors and cytokines present in the bone marrow microenvironment. Among them, IL-6 triggers the signal downst...

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Detalles Bibliográficos
Autores principales: Canovas Nunes, Sara, Manzoni, Martina, Pizzi, Marco, Mandato, Elisa, Carrino, Marilena, Quotti Tubi, Laura, Zambello, Renato, Adami, Fausto, Visentin, Andrea, Barilà, Gregorio, Trentin, Livio, Manni, Sabrina, Neri, Antonino, Semenzato, Gianpietro, Piazza, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811530/
https://www.ncbi.nlm.nih.gov/pubmed/29440639
http://dx.doi.org/10.1038/s41408-018-0053-z