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The small GTPase RhoU lays downstream of JAK/STAT signaling and mediates cell migration in multiple myeloma
Multiple myeloma is a post-germinal center B-cell neoplasm, characterized by the proliferation of malignant bone marrow plasma cells, whose survival and proliferation is sustained by growth factors and cytokines present in the bone marrow microenvironment. Among them, IL-6 triggers the signal downst...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811530/ https://www.ncbi.nlm.nih.gov/pubmed/29440639 http://dx.doi.org/10.1038/s41408-018-0053-z |