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Molecular determinants of Guanylate Cyclase Activating Protein subcellular distribution in photoreceptor cells of the retina

Retinal guanylate cyclase (RetGC) and guanylate cyclase activating proteins (GCAPs) play an important role during the light response in photoreceptor cells. Mutations in these proteins are linked to distinct forms of blindness. RetGC and GCAPs exert their role at the ciliary outer segment where phot...

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Detalles Bibliográficos
Autores principales: López-Begines, Santiago, Plana-Bonamaisó, Anna, Méndez, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811540/
https://www.ncbi.nlm.nih.gov/pubmed/29440717
http://dx.doi.org/10.1038/s41598-018-20893-1