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Mammalian Cells Undergo Endoreduplication in Response to Lactic Acidosis

Polyploidization, a common event during the evolution of different tumours, has been proposed to confer selective advantages to tumour cells by increasing the occurrence of mutations promoting cancer progression and by conferring chemotherapy resistance. While conditions leading to polyploidy in can...

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Detalles Bibliográficos
Autores principales: Tan, Zhihao, Chu, De Zhi Valerie, Chan, Yong Jie Andrew, Lu, Yi Ena, Rancati, Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811548/
https://www.ncbi.nlm.nih.gov/pubmed/29440645
http://dx.doi.org/10.1038/s41598-018-20186-7