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Mammalian Cells Undergo Endoreduplication in Response to Lactic Acidosis
Polyploidization, a common event during the evolution of different tumours, has been proposed to confer selective advantages to tumour cells by increasing the occurrence of mutations promoting cancer progression and by conferring chemotherapy resistance. While conditions leading to polyploidy in can...
Autores principales: | Tan, Zhihao, Chu, De Zhi Valerie, Chan, Yong Jie Andrew, Lu, Yi Ena, Rancati, Giulia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811548/ https://www.ncbi.nlm.nih.gov/pubmed/29440645 http://dx.doi.org/10.1038/s41598-018-20186-7 |
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