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Functional Variants Identified Efficiently through an Integrated Transcriptome and Epigenome Analysis
Although genome-wide association studies (GWAS) have identified numerous genetic loci associated with complex diseases, the underlying molecular mechanisms of how these loci contribute to disease pathogenesis remain largely unknown, due to the lack of an efficient strategy to identify these risk var...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811556/ https://www.ncbi.nlm.nih.gov/pubmed/29440655 http://dx.doi.org/10.1038/s41598-018-21024-6 |