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Functional Variants Identified Efficiently through an Integrated Transcriptome and Epigenome Analysis

Although genome-wide association studies (GWAS) have identified numerous genetic loci associated with complex diseases, the underlying molecular mechanisms of how these loci contribute to disease pathogenesis remain largely unknown, due to the lack of an efficient strategy to identify these risk var...

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Detalles Bibliográficos
Autores principales: Meng, Fanlin, Yuan, Guohong, Zhu, Xiurui, Zhou, Yiming, Wang, Dong, Guo, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811556/
https://www.ncbi.nlm.nih.gov/pubmed/29440655
http://dx.doi.org/10.1038/s41598-018-21024-6