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Chronic exposure to low dose of bisphenol A impacts on the first round of spermatogenesis via SIRT1 modulation

Spermatogenesis depends on endocrine, autocrine and paracrine communications along the hypothalamus-pituitary-gonad axis. Bisphenol A (BPA), an estrogen-mimic endocrine disrupting chemical, is an environmental contaminant used to manufacture polycarbonate plastics and epoxy resins with toxic effects...

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Detalles Bibliográficos
Autores principales: Chianese, Rosanna, Viggiano, Andrea, Urbanek, Konrad, Cappetta, Donato, Troisi, Jacopo, Scafuro, Marika, Guida, Maurizio, Esposito, Grazia, Ciuffreda, Loreta Pia, Rossi, Francesco, Berrino, Liberato, Fasano, Silvia, Pierantoni, Riccardo, De Angelis, Antonella, Meccariello, Rosaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811609/
https://www.ncbi.nlm.nih.gov/pubmed/29440646
http://dx.doi.org/10.1038/s41598-018-21076-8