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Chronic exposure to low dose of bisphenol A impacts on the first round of spermatogenesis via SIRT1 modulation
Spermatogenesis depends on endocrine, autocrine and paracrine communications along the hypothalamus-pituitary-gonad axis. Bisphenol A (BPA), an estrogen-mimic endocrine disrupting chemical, is an environmental contaminant used to manufacture polycarbonate plastics and epoxy resins with toxic effects...
Autores principales: | Chianese, Rosanna, Viggiano, Andrea, Urbanek, Konrad, Cappetta, Donato, Troisi, Jacopo, Scafuro, Marika, Guida, Maurizio, Esposito, Grazia, Ciuffreda, Loreta Pia, Rossi, Francesco, Berrino, Liberato, Fasano, Silvia, Pierantoni, Riccardo, De Angelis, Antonella, Meccariello, Rosaria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811609/ https://www.ncbi.nlm.nih.gov/pubmed/29440646 http://dx.doi.org/10.1038/s41598-018-21076-8 |
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