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A chemoenzymatic process for amide bond formation by an adenylating enzyme-mediated mechanism
Amide bond formation serves as a fundamental reaction in chemistry, and is practically useful for the synthesis of peptides, food additives, and polymers. However, current methods for amide bond formation essentially generate wastes and suffer from poor atom economy under harsh conditions. To solve...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811625/ https://www.ncbi.nlm.nih.gov/pubmed/29440726 http://dx.doi.org/10.1038/s41598-018-21408-8 |