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A chemoenzymatic process for amide bond formation by an adenylating enzyme-mediated mechanism

Amide bond formation serves as a fundamental reaction in chemistry, and is practically useful for the synthesis of peptides, food additives, and polymers. However, current methods for amide bond formation essentially generate wastes and suffer from poor atom economy under harsh conditions. To solve...

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Detalles Bibliográficos
Autores principales: Hara, Ryotaro, Hirai, Kengo, Suzuki, Shin, Kino, Kuniki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811625/
https://www.ncbi.nlm.nih.gov/pubmed/29440726
http://dx.doi.org/10.1038/s41598-018-21408-8