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S100A9 aggravates bleomycin-induced dermal fibrosis in mice via activation of ERK1/2 MAPK and NF-κB pathways

OBJECTIVE(S): This study aims to investigate the pathogenicity and possible mechanisms of S100A9 function in mice models of scleroderma. MATERIALS AND METHODS: The content of S100A9 in the skin tissues of mice with scleroderma was determined. Different concentrations of bleomycin (BLM) and S100A9 we...

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Detalles Bibliográficos
Autores principales: Xu, Xue, Chen, Zhiyong, Zhu, Xiaoxia, Wang, Dandan, Liang, Jun, Zhao, Cheng, Feng, Xuebing, Wang, Jiucun, Zou, Hejian, Sun, Lingyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811759/
https://www.ncbi.nlm.nih.gov/pubmed/29456817
http://dx.doi.org/10.22038/IJBMS.2018.19987.5255