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Pharmacokinetics of a Novel Anagrelide Extended‐Release Formulation in Healthy Subjects: Food Intake and Comparison With a Reference Product

Anagrelide is an established therapy for essential thrombocythemia. Common adverse effects have been linked to peak plasma concentrations of anagrelide and its 3OH metabolite. Our study was performed to investigate the pharmacokinetics (PK) of a novel anagrelide extended‐release (AER) formulation an...

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Detalles Bibliográficos
Autores principales: Petrides, Petro E., Schoergenhofer, Christian, Widmann, Rudolf, Jilma, Bernd, Klade, Christoph S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811889/
https://www.ncbi.nlm.nih.gov/pubmed/28301098
http://dx.doi.org/10.1002/cpdd.340