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Mitotane treatment in patients with metastatic testicular Leydig cell tumor associated with severe androgen excess

Mitotane (o,p′DDD) is established in the adjuvant and advanced-stage treatment of adrenocortical carcinoma and counteracts both tumor growth and tumor-related steroid production. Both the adrenal glands and the gonads are steroidogenically active organs and share a common embryogenic origin. Here, w...

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Detalles Bibliográficos
Autores principales: Chortis, Vasileios, Johal, Nicholas J, Bancos, Irina, Evans, Matthew, Skordilis, Kassiani, Guest, Peter, Cullen, Michael H, Porfiri, Emilio, Arlt, Wiebke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811932/
https://www.ncbi.nlm.nih.gov/pubmed/29330226
http://dx.doi.org/10.1530/EJE-17-0542