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Mitotane treatment in patients with metastatic testicular Leydig cell tumor associated with severe androgen excess
Mitotane (o,p′DDD) is established in the adjuvant and advanced-stage treatment of adrenocortical carcinoma and counteracts both tumor growth and tumor-related steroid production. Both the adrenal glands and the gonads are steroidogenically active organs and share a common embryogenic origin. Here, w...
Autores principales: | Chortis, Vasileios, Johal, Nicholas J, Bancos, Irina, Evans, Matthew, Skordilis, Kassiani, Guest, Peter, Cullen, Michael H, Porfiri, Emilio, Arlt, Wiebke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bioscientifica Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811932/ https://www.ncbi.nlm.nih.gov/pubmed/29330226 http://dx.doi.org/10.1530/EJE-17-0542 |
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