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Conservation of alternative splicing in sodium channels reveals evolutionary focus on release from inactivation and structural insights into gating
KEY POINTS: Sodium channels are critical for supporting fast action potentials in neurons; even mutations which cause small changes in sodium channel activity can have devastating consequences for the function of the nervous system. Alternative splicing also changes the activity of sodium channels,...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811987/ https://www.ncbi.nlm.nih.gov/pubmed/28621020 http://dx.doi.org/10.1113/JP274693 |