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Efficacy of oral metformin in a patient with metastatic adrenocortical carcinoma: Examination of mechanisms and therapeutic implications

Although rare, adrenocortical carcinoma is among the most common tumors found in children with Li-Fraumeni syndrome and Li-Fraumeni-like syndrome, associated with germ-line mutations in the TP53 gene. In southern Brazil, one form of Li-Fraumeni syndrome, associated with childhood adrenocortical carc...

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Detalles Bibliográficos
Autores principales: Peixoto, RD, Gomes, LM, Sousa, TT, Racy, DJ, Shigenaga, M, Nagourney, RA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811989/
https://www.ncbi.nlm.nih.gov/pubmed/31508193
http://dx.doi.org/10.1177/2036361317749645